Chronic Mental Diseases

Chronic mental diseases (CMD), such as schizophrenia, are progressive genetic disorders characterized by delusions, paranoia and disorganized thinking. An imbalance in protein production versus clearance is a hallmark of dysfunctional neurons, leading to abnormal deposition of protein aggregates. The gene DISC1 (Disrupted-in-schizophrenia 1)  is considered among the most promising candidate genes for causing CMD.