Preeclampsia

Preeclampsia is a pregnancy disorder of unknown cause and a leading contributor to morbidity and mortality of mothers and newborn babies. The only treatment for preeclampsia is delivery, which makes it the leading cause of induced pre-term birth. In 2014, a strong correlation between abnormal protein aggregation and preeclampsia was reported. Among the proteins that were found to form abnormal aggregates were ceruloplasmin, immunoglobulin light chain (similar to primary amyloidosis), SERPINA1, albumin, interferon-inducible protein 6-16, and amyloid β-protein precursor (APP).