Spinal Cord Injury And Traumatic Brain Injury
- Age-Related Macular Degeneration
- Alzheimer’s Disease
- Amyotrophic Lateral Sclerosis
- Autism Spectrum Disorder
- Chronic Mental Diseases
- Chronic Traumatic Encephalopathy
- Conjunctival Amyloidosis
- Corticobasal Degeneration
- Creutzfeldt–Jakob Disease
- Dementia With Lewy Bodies
- Dentatombral-Pallidoluysian Atrophy
- Desmin-Related Cardiomyopathy
- Dialysis-Related Amyloidosis
- Familial Alzheimer’s Disease
- Familial Amyloidotic Cardiomyopathy
- Familial Amyloidotic Polyneuropathy
- Familial Amyotrophic Lateral Sclerosis
- Familial British Dementia
- Familial Danish Dementia
- Familial Fatal Insomnia
- Familial Mediterranean Fever
- Familial Oculoleptomeningel Amyloidosis
- Familial Parkinson’s Disease
- Finnish Hereditary Systemic Amyloidosis
- Frontotemporal Dementia
- Gerstmann–Sträussler–Scheinker Syndrome
- HIV Infection
- Hereditary Cerebral Amyloid Angiopathy
- Hereditary Non-Neuropathic Systemic Amyloidosis
- Hereditary Renal Amyloidosis
- Huntington’s Disease
- Inclusion Body Myositis
- Insulin-Related Amyloidosis
- Isolated Atrial Amyloidosis
- Medullary Carcinoma Of The Thyroid
- Multiple Systems Atrophy
- Parkinson’s Disease
- Pick’s Disease
- Preeclampsia
- Primary Amyloidosis
- Progressive Supranuclear Palsy
- Prostatic Amyloidosis
- Pure Autonomic Failure
- Senile Systemic Amyloidosis
- Spinal And Bulbar Muscular Atrophy
- Spinal Cord Injury And Traumatic Brain Injury
- Spinocerebellar Ataxia Types 1, 2, 3, 6, 7, And 17
- Systemic (Reactive) Aa Amyloidosis
- Type-2 Diabetes Mellitus
Spinal cord injury (SCI) and traumatic brain injury (TBI) are conditions in which the spinal cord or the brain, respectively, suffer trauma, leading to symptoms that range from mild to very severe. Interestingly, in these conditions, certain proteins, including Aβ, tau, α-synuclein, and TDP-43 aggregate abnormally and form insoluble deposits in the affected tissue. It is not clear to what extent the abnormal protein aggregation and deposition contribute to the neuronal degeneration and loss in SCI and TBI, yet recent animal studies suggest that preventing the abnormal protein aggregation may help neurons to survive.